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. 2021 Dec 3;37(12):110126. doi: 10.1016/j.celrep.2021.110126

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© 2021 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Blood IFP35 reflected the turnover of individuals with COVID-19

(A and B) Serum IFP35 (A) and IL-6 (B) in 8 severely ill individuals with COVID-19 before and after treatment. Significance was calculated by two-tailed Wilcoxon matched-pairs signed rank test (^∗p < 0.05, ^∗∗p < 0.01).

(C) Chest computed tomography (CT) in a severely ill individual with COVID-19 before and after treatment. The bilateral, multiple, patchy, ground-glass opacities before treatment are indicated by red arrows and were located in the same position after treatment when the lesions were improved.

(D and E) IFP35 (D) and IL-6 (E) in the sera of individuals in group 2. Data from 11 deceased individuals and 26 improved individuals are shown as orange dots and blue dots, respectively.