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. 2021 Nov 19;11:740762. doi: 10.3389/fonc.2021.740762

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Copyright © 2021 Chen, Lai, Ye and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The overall downstaging success rate of hepatic resection of HCC (A), pooled downstaging rate stratified by TACE and CT (B), pooled downstaging rate stratified by mono/multitherapy (C); pooled downstaging rate stratified by cirrhosis included/excluded (D). TACE, transarterial chemoembolization; CT, chemotherapy.