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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Neuron. 2021 Sep 29;109(23):3736–3757. doi: 10.1016/j.neuron.2021.09.004

Figure 5. BDNF signaling is deployed at different times and in different locales to instruct a range of somatosensory neuron subtype axonal morphologies and functions.

Figure 5.

The neurotrophic factor BDNF (green dots) is expressed in several end organ niches in the periphery, including cells of glabrous skin, mammary gland, and hairy skin. The BDNF receptor TrkB receptor is expressed in subsets of developing axons (black). Mutants lacking either BDNF in the periphery or the TrkB receptor in axons exhibit deficits in ending morphology and function, in each of these cases.