Skip to main content
. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Epilepsia. 2021 Oct 7;62(12):3091–3104. doi: 10.1111/epi.17090

Figure 6. OV329 produces a dose-dependent increase in the responder rate concerning the afterdischarge threshold (ADT) and the generalized seizure threshold (GST).

Figure 6

Responders (marked by a continuous line) were defined as showing at least 25% increase in ADT (A) or GST (B) after OV329 treatment compared to saline (S) control. At 40 mg/kg OV329, none of the animals expressed generalized motor seizures, and the GST was set at 1000 μA (B) for data evaluation.