Table 1.

Experimental Conditions

	Mild CPB (n=10)		Severe CPB (n=10)
	Mean	SD	Mean	SD	p value
Temperature (°C)
Pre CPB	36.2	1.0	36.2	0.8	0.9999
Cooling	33.8	0.3	26.6	0.7	<0.0001*
FF or CA	33.1	0.3	24.7	0.8	<0.0001*
Rewarming	36.4	0.9	35.6	0.9	0.2399
3hrs	37.0	0.8	37.0	0.5	0.9999
MBP (mmHg)
Pre CPB	83.9	19.6	80.7	15.0	0.9999
Cooling	99.7	14.1	95.5	12.9	0.9999
FF or CA	113.5	17.1	5.4	1.9	<0.0001*
Rewarming	130.4	18.3	114.9	17.9	0.3526
3hrs	92.8	14.9	87.1	13.0	0.9999
pH
Pre CPB	7.585	0.098	7.582	0.082	0.9999
Cooling	7.489	0.036	7.471	0.042	0.9999
Rewarming	7.546	0.033	7.458	0.034	<0.0001*
3hrs	7.605	0.047	7.570	0.053	0.5423
PaCO2 (mmHg)
Pre CPB	32.1	6.7	33.3	6.5	0.9999
Cooling	42.8	3.1	41.8	2.2	0.9999
Rewarming	41.5	3.4	39.3	2.7	0.5092
3hrs	32.4	3.8	30.4	3.3	0.8892
Hematocrit (%)
Pre CPB	35.5	3.6	36.9	2.3	0.9999
Cooling	34.1	1.5	33.9	1.6	0.9999
Rewarming	32.4	1.8	33.7	1.8	0.4967
3hrs	36.9	3.7	33.7	1.9	0.1200
TOI
Pre CPB	47.7	5.3	47.2	2.4	0.9999
Cooling	58.1	3.4	64.7	5.4	0.0236*
FF or CA	57.6	2.6	34.7	4.4	<0.0001*
Rewarming	53.7	2.8	53.2	1.6	0.9999
3hrs	48.9	1.9	47.3	4.1	0.9999
Lactate (mmol/l)
Pre CPB	1.4	0.4	1.4	0.4	0.9999
Cooling	2.4	0.8	2.5	0.5	0.9999
Rewarming	1.8	0.9	6.9	1.3	<0.0001*
3hrs	2.0	0.9	5.4	1.4	<0.0001*
Leukocyte (103/μL)
Pre CPB	5.4	1.4	6.9	1.2	0.0787
Cooling	5.7	1.8	5.3	1.4	0.9999
Rewarming	5.9	1.9	7.8	3.3	0.5948
3hrs	11.8	4.5	14.0	3.7	0.9560

CPB, cardiopulmonary bypass; MAP, mean arterial pressure; TOI, tissue oxygen index.

^*Statistically significant.