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. 2021 Nov 29;53(11):1683–1688. doi: 10.1038/s12276-021-00711-x

Fig. 2. Epigenetic pathways inhibiting cryptic transcription.

Fig. 2

Cryptic transcriptional initiation within the ORF is suppressed by cooperation between H2Bub and the FACT complex, H3K4me2 and the histone (poly)sumoylation-mediated Set3 HDAC complex, and the H3K36me3-dependent association of the Rpd3S complex, DNMT3B, KDM5B, or FACT complex.