Table 1:
Baseline Patient Characteristics, n=65,673
| Pre-Guidelines (n=31145) | Post-Guidelines (n=34528) | |
|---|---|---|
| Sex, n (%) | ||
| Female | 19446 (62.4%) | 21412 (62.0%) |
| Male | 11699 (37.6%) | 13116 (38.0%) |
| Age Category, years, n (%) | ||
| <25 | 6844 (22.0%) | 7604 (22.0%) |
| 25–35 | 12103 (38.9%) | 12950 (37.5%) |
| 35–50 | 10232 (32.9%) | 11731 (34.0%) |
| >50 | 1966 (6.3%) | 2243 (6.5%) |
| Enrollment CD4 performed, n (%) | 16055 (51.5%) | 10014 (29.0%) |
| Enrollment CD4 Category*, cells/μL, n (%) | ||
| <200 | 5697 (35.5%) | 3300 (33.0%) |
| 200–350 | 4118 (25.6%) | 2594 (25.9%) |
| 350–500 | 2903 (18.1%) | 1848 (18.5%) |
| >500 | 3337 (20.8%) | 2272 (22.7%) |
| Enrollment WHO Stage, n (%) | ||
| 1 | 13355 (42.9%) | 17889 (51.8%) |
| 2 | 3658 (11.7%) | 3459 (10.0%) |
| 3 | 5988 (19.2%) | 4179 (12.1%) |
| 4 | 372 (1.2%) | 175 (0.5%) |
| Unknown | 7772 (25.0%) | 8826 (25.6%) |
| TB in past year, n (%) | 1567 (5.0%) | 1865 (5.4%) |
| Pregnant/Breastfeeding at Enrollment, n (%) | 3470 (17.8%) | 3160 (14.8%) |
| Eligibility Category**, n (%) | ||
| Always | 17499 (56.2%) | 13022 (37.7%) |
| Newly | 2571 (8.3%) | 1888 (5.5%) |
| Unknown | 11075 (35.6%) | 19618 (56.8%) |
| Marital Status, n (%) | ||
| Single | 3994 (12.8%) | 4342 (12.6%) |
| Married | 15519 (49.8%) | 16381 (47.4%) |
| Divorced | 4226 (13.6%) | 4295 (12.4%) |
| Widowed | 2145 (6.9%) | 1935 (5.6%) |
| Unknown | 5261 (16.9%) | 7575 (21.9%) |
| Education, n (%) | ||
| None | 1667 (5.4%) | 1679 (4.9%) |
| Primary | 8675 (27.9%) | 8599 (24.9%) |
| Secondary | 14506 (46.6%) | 16056 (46.5%) |
| University | 1256 (4.0%) | 1349 (3.9%) |
| Unknown | 5041 (16.2%) | 6845 (19.8%) |
| Facility Type***, n (%) | ||
| Small Health Center | 1918 (6.2%) | 3810 (11.0%) |
| Medium Health Center | 4136 (13.3%) | 4661 (13.5%) |
| Large Health Center | 21487 (69.0%) | 21316 (61.7%) |
| Hospital | 3604 (11.6%) | 4741 (13.7%) |
| Province | ||
| Lusaka | 28544 (91.6%) | 31284 (90.6%) |
| Western | 2601 (8.4%) | 3244 (9.4%) |
*
Among those not missing an enrollment CD4 count.
**
Eligibility subgroups were defined by whether patients would have been eligible for ART according to both the 2014 and 2017 guidelines (“Always Eligible”) or only the 2017 guidelines (“Newly Eligible”) at time of enrollment, regardless of the time period in which they actually enrolled. These were defined using data captured in the EHR; individuals with missing CD4 measurements who did not clearly meet other eligibility criteria were categorized as “Unknown”.
***
Small Health Center: <500 patients, Medium Health Center: 500–2500 patients, Large Health Center: >2500 patients