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. 2021 Nov 26;53(11):1674–1682. doi: 10.1038/s12276-021-00709-5

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© The Author(s) 2021

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Fig. 1 — O-GlcNAcylation is a posttranslational modification that attaches O-GlcNAc moieties to serine or threonine residues of cellular proteins. O-GlcNAcylation can regulate important cellular processes such as gene expression, signal transduction, cell cycle, nutrient sensing, protein homeostasis, cellular stress response, and neuronal function.