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. Author manuscript; available in PMC: 2022 Dec 3.
Published in final edited form as: Circ Res. 2021 Oct 27;129(12):e215–e233. doi: 10.1161/CIRCRESAHA.121.319066

Figure 6. SMC-specific genetic FAK-KD mice did not upregulate injury-induced DNMT3A and 5-mC expression protecting from neointima formation.

Figure 6.

Representative immunofluorescence staining of FAK-WT and FAK-KD femoral arteries 2 weeks postinjury for FAK, pY397 FAK, DNMT3A, DNMT3B, 5-mC and ACTA2 (n=4). FAK-KD in SMCs from the injured group exhibited a low DNMT3A and 5-mC as observed in sham. Merge 1, green and red; Merge 2, green, red, and blue (DAPI) were merged. Dashed line in image marks the elastic lamina. White line indicates endothelial layer. L, lumen. Scale bars: 20 μm.