Figure 2: Single-cell deconvolution of bulk RNA-seq from aspirin exposed colon organoids.

Nominally significant (P=0.05; light blue) and FDR corrected (q=0.10; dark blue) DEGs were overlaid with known cell markers of colon cell types as identified through scRNA-seq. Positive values indicate the number of genes displaying increased expression, while negative values indicate number of genes with reduced expression in A) aspirin treated organoids or B) regular users of aspirin.