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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: J Am Soc Mass Spectrom. 2021 Oct 29;32(12):2746–2754. doi: 10.1021/jasms.1c00189

Figure 2.

Figure 2.

Human collagen peptides with mouse homology are more abundant in hydrogel injection sites. (a) Total number of putative human peptide identifications from hydrogel injected tissues as a function of collagen subtype for collagens injected. (b) Representative collagen type 1 peaks as visualized in rhCI injected hearts as compared to PBS controls. Average intensity levels measured between all samples studied are shown in (c). (d) Representative collagen type 3a1 peaks as visualized in rhCIII injected hearts as compared with PBS controls. Average intensity levels measured between all samples studied are shown in (e). n = 3. Six tissue sections were visualized for each biological replicate. Different representative samples are used to show reproducibility across n’s. Peptides shown in panel d (left) represent nearest identified putative peptides from previously acquired human databases.