Skip to main content
. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: J Am Soc Mass Spectrom. 2021 Oct 29;32(12):2746–2754. doi: 10.1021/jasms.1c00189

Figure 4.

Figure 4.

Collagen targeted proteomics investigates endogenous mouse ECM remodeling. (a) Venn Diagram showing the number of proteins identified in PBS control, rhCI hydrogel, and rhCIII hydrogel samples. (b) Hierarchical clustering of protein level fold change (infarct/remote) values for each treatment group. (c) Hierarchical clustering of LC-MS/MS identified mouse peptides mapped via MALDI IMS studies. ROI intensity for infarct and remote is shown for each treatment group. (d) Representative image of a COL3A1 peptide that was differentially abundant in PBS Ctrl vs hydrogel treatment, mapped via MALDI IMS.