Table 2.

Results of multivariable multinomial model for LT waitlist outcomes (N=1,661)

	WL mortality		Spontaneous survival
Variable	RRR* (95% CI)	p value	RRR* (95% CI)	p value
ALF etiology		<0.001		<0.001
APAP	---		---
HBV	0.43(0.27–0.67)		0.05(0.01–0.16)
AIH	0.43(0.26–0.68)		0.04(0.01–0.10)
DILI	0.65(0.44–0.97)		0.15(0.08–0.28)
Female	0.99(0.72–1.36)	0.944	0.81(0.52–1.28)	0.367
Age, per year	1.01(1.00–1.02)	0.238	0.99(0.97–1.00)	0.077
Race/ethnicity		0.990		0.267
White	---		---
Black	1.04(0.72–1.52)		0.55(0.28–1.08)
Hispanic	0.91(0.55–1.50)		1.07(0.57–2.01)
Asian	0.96(0.54–1.71)		0.40(0.11–1.42)
Other	1.11(0.41–2.95)		1.29(0.34–4.91)
MELD, per point	1.03(1.01–1.04)	0.004	0.92(0.90–0.94)	<0.001
Clinical Factors at WL
Grade 3–4 encephalopathy	1.69(1.20–2.38)	0.003	0.65(0.44–0.97)	0.035
Ascites present	1.00(0.75–1.33)	0.988	0.61(0.40–0.95)	0.027
Mechanical ventilation	2.08(1.52–2.86)	<0.001	0.35(0.23–0.52)	<0.001
Dialysis	0.83(0.54–1.30)	0.417	1.45(0.75–2.82)	0.274
Era		0.195		0.810
2002–2007	---		---
2008–2013	0.75(0.55–1.03)		0.87(0.57–1.33)
2014–2019	0.83(0.58–1.18)		0.97(0.60–1.57)

Abbreviations: APAP – acetaminophen; DILI – drug induced liver injury; AIH – autoimmune hepatitis; HBV – hepatitis B virus; LT – liver transplantation; WL – waitlist; MELD – Model for End-Stage Liver Disease

^*Reference outcome is LT