Table 1.
The information of the crystal structure and input compositions of human glucokinase used (PDB ID-1V4S)
| The details of crystal structure (1V4S): | ||||||
| Title: | Crystal structure of human glucokinase | |||||
| DOI: | 10.2210/pdb1V4S/pdb | |||||
| Authors: | Kamata, K., Mitsuya, M., Nishimura, T., Eiki, J., Nagata, Y | |||||
| Deposited on: | 30-03-2004 | |||||
| Resolution: | 2.30 Å(reported) | |||||
| Classification: | Transferase | |||||
| Organism(s): | Homo sapiens | |||||
| Expression System: | Escherichia coli | |||||
| Method: | X-Ray diffraction | |||||
| Residues | Atoms | |||||
| The entry composition of 1V4S: | ||||||
| Total | C | N | O | S | Na/F | |
| Molecule 1 was a protein called glucokinase isoform 2 | ||||||
| 448 | 3505 | 2178 | 609 | 686 | 32 | 0 |
| Molecule 2 was alpha-D-glucopyranose (three-letter code: GLC) (formula: C6H12O6) | ||||||
| 1 | 12 | 6 | 0 | 6 | 0 | 0 |
| Molecule 3 was SODIUM ION (three-letter code: NA) (formula: Na) | ||||||
| 1 | 1 | 0 | 0 | 0 | 0 | 1 (Na) |
| Molecule 4 was native ligand 5-(1-methyl-1H-imidazol-2-ylthio)-2-amino-4-fluoro-N-(thiazol-2-yl)benzamide (three-letter code: MRK) (formula: C14H12FN5OS2) | ||||||
| 1 | 23 | 14 | 5 | 1 | 2 | 1 (F) |
| Molecule 5 was water | ||||||
| 149 | 149 | 0 | 0 | 149 | 0 | 0 |
Where, C carbon; N nitrogen; O oxygen; S sulphur; Na sodium; F fluorine