Table 2.
Incidences and hazard ratios associated with pulse pressure quartile for progression of chronic kidney disease.
| Incident rate (per 1000 person-years) | Crude HR (95% CI) | p-value | Adjusted HR | p-value | |
|---|---|---|---|---|---|
| Progression of CKD | |||||
| PP (per 10 mmHg) | – | 1.30 (1.20–1.42) | < 0.001 | 1.17 (1.06–1.29) | 0.002 |
| PP quartile | |||||
| Q1 (≤ 48) | 31.9 (44/1379) | 1.00 (reference) | < 0.001* | 1.00 (reference) | 0.003* |
| Q2 (49–56) | 40.5 (54/1333) | 1.14 (0.85–1.89) | 1.14 (0.74–1.76) | ||
| Q3 (57–65) | 47.2 (55/1166) | 1.47 (0.99–2.18) | 1.35 (0.88–2.06) | ||
| Q4 (≥ 66) | 90.1 (88/977) | 2.72 (1.89–3.91) | 1.87 (1.23–2.83) | ||
PP Pulse Pressure, CKD Chronic kidney disease, HR Hazard ratio, CI confidence interval. Adjusted HRs were obtained, controlling for age, sex, BP-lowering medication, diabetes, dyslipidemia, hyperuricemia, obesity, smoking, drinking, and baseline eGFR and proteinuria.
*p for trend.