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. 2021 Dec 2;11:23275. doi: 10.1038/s41598-021-02809-8

Table 3.

Comparison of the discrimination of prediction for the progression of CKD between targeted BP, PP, and the combination of PP and targeted BP.

Harrel’s C-index Difference from model 1 p-value
Model 1 0.7327 (0.6986–0.7668)
Model 2 0.7356 (0.7010–0.7702) 0.0029 (− 0.0076–0.0135) 0.588
Model 3 0.7330 (0.6988–0.7672) 0.0003 (− 0.0043–0.0049) 0.854

Model 1: conventional targeted BP (< 130/80 mmHg for those with diabetes or proteinuria and < 140/90 mmHg); model 2: PP ≥ 66 mmHg; model 3: combination of PP (< 66 or ≥ 66) and/or targeted BP.

Other variables for adjustment were age, sex, BP-lowering medication, diabetes, dyslipidemia, hyperuricemia, obesity, smoking, drinking, and baseline eGFR and proteinuria.