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. 2021 Dec 2;11(12):192. doi: 10.1038/s41408-021-00587-0

Table 1.

Main results of the two clinical studies used for this position paper [16, 17].

Clinical series
Variable Granell et al. [16] Ravi et al. [17]
Number of patients 482a 176b
Age (median; years) 69 62
Sex (M/F); % 42/58 56/44
Patients with CPC; n 100 176
Distribution according CPC (n; %)c
1–4% 83 (83%) 54 (31%)
5–20% 12 (12%) 63 (36%)
More than 20% 5 (5%) 59 (34%)
Median overall survival according to CPC; months
0% 47 53
1-4% 50 17
5–20% 6 13
More than 20% 14 13

aTotally, 382 patients (included in the number in the table) without circulating plasma cells were used as controls.

bTotally, 9724 patients (not included in the number in the table) diagnosed in the same period without circulating plasma cells at diagnosis were used as controls.

cConsidering only patients with circulating plasma cells.

CPC circulating plasma cells.