TABLE 1.
Population | Clone number |
Clonal MIC (fold increase)
|
pH-induced fold increase | |
pH 6.5 | pH 7.5 | |||
Biofilm pH 6.5 population 1 (B1) | B11 | 64 | 4 | 16 |
B12 | 80 | 4 | 20 | |
B13 | 64 | 4 | 16 | |
B14 | 94 | 6 | 15.7 | |
| ||||
Biofilm pH 6.5 population 2 (B2) | B21 | 96 | 10 | 9.6 |
B22 | 96 | 24 | 4 | |
B23 | 96 | 24 | 4 | |
B24 | 128 | 32 | 4 | |
| ||||
Biofilm pH 6.5 population 3 (B3) | B31 | 6 | 4 | 1.5 |
B32 | 4 | 4 | 1 | |
B33 | 6 | 4 | 1.5 | |
B34 | 8 | 4 | 2 |
∗Ceftazidime MIC against PA14 ancestor: 1.25 μg/mL.