Table 1.
Intervention group (n=45) |
Control group (n=44) |
P value (Student t-test or χ² test) |
|
Age (years) | 59.4±3.9 | 61.7±4.0 | 0.407* |
Body mass index (kg/m2) | 27.2±1.4 | 28.3±1.7 | 0.323* |
No of men (n) | 30 (66.7%) | 25 (56.8%) | 0.339† |
Social level (n) | |||
1 | 14 (31.1%) | 19 (43.2%) | 0.419† |
2 | 11 (24.4%) | 7 (15.9%) | |
3 | 20 (44.4%) | 18 (40.9%) | |
Kidney failure (n) | 6 (13.3%) | 8 (18.2%) | 0.530† |
Liver failure (n) | 0 (0%) | 1 (2.3%) | NA |
No of total chronic diseases (n) | |||
1 | 11 (24.4%) | 8 (18.2%) | 0.613† |
2 | 14 (31.1%) | 12 (27.3%) | |
>2 | 20 (44.4%) | 24 (54.5%) | |
No of diseases involved in the study (n) | |||
1 | 37 (82.2%) | 36 (81.8%) | 0.960† |
Hypertension | 24 (53.3%) | 22 (50.0%) | 0.613† |
Type 2 diabetes | 5 (11.1%) | 7 (15.9%) | |
Hypercholesterolaemia | 8 (17.8%) | 7 (15.9%) | |
2 | 7 (15.6%) | 8 (18.2%) | 0.777† |
Hypertension + type 2 diabetes | 6 (13.3%) | 6 (13.6%) | 1† |
Hypertension + hypercholesterolaemia | 1 (2.2%) | 0 (0.0%) | NA |
Type 2 diabetes + hypercholesterolaemia | 0 (0.0%) | 2 (4.5%) | NA |
3 | 1 (2.2%) | 0 (0.0%) | NA |
No of different drugs prescribed | 5.0±0.8 | 6.2±1.2 | 0.118* |
Adjusted no of different drugs prescribed (n) | |||
<5 | 18 (40.0%) | 18 (40.9%) | 0.930† |
≥5 | 27 (60.0%) | 26 (59.1%) | |
Side effects (n) | 9 (20%) | 11 (25.0%) | 0.572† |
Adherence score | 2.0±0.4 | 2.2±0.4 | 0.501* |
Patients with hypertension (n) | 32 (71.1%) | 28 (63.6%) | 0.452† |
Used as primary outcome (n) | 27 (60.0%) | 28 (63.6%) | 0.724† |
Patients with type 2 diabetes (n) | 12 (26.7%) | 15 (34.1%) | 0.446† |
Used as primary outcome (n) | 9 (20.0%) | 7 (15.9%) | 0.615† |
Patients with hypercholesterolaemia (n) | 10 (22.2%) | 9 (20.5%) | 0.839† |
Used as primary outcome (n) | 9 (20%) | 9 (20.5%) | 0.957† |
Lost to follow-up (n) | 11 (24.4%) | 5 (11.4%) | 0.108† |
Data are expressed as proportion of patients and number of patients for dichotomous variables, and as mean±95% CI for continuous variables.
*Student t-test.
†χ2 test.