Table 5.
Therapeutic outcome | Intervention group | Control group | P value | RRR or RBI (95% CI) |
NNT (95% CI) |
||
No of DRPs N (%) |
No of patients N (%) |
No of DRPs N (%) |
No of patients N (%) |
||||
Number of DRPs during hospitalisation | 545 | 63 | 517 | 60 | NA | NA | |
Resolved or improved | 132 (24.2) | 30 (47.6) | 64 (12.4) | 14 (23.3) | 0.01 | 104.3% (RBI) (20.5% to 245.6%) |
4.1 (2.5 to 12.7) |
Prevented | 240 (44.0) | 42 (66.7) | 35 (6.8) | 6 (10.0) | <0.0001 | 567% (RBI) (205.9% to 1352.8%) |
1.8 (1.4 to 2.5) |
Not changed | 161 (29.5) | 23 (36.5) | 403 (77.9) | 56 (93.3) | <0.0001 | 60.9% (RRR) (55.5% to 71.9%) |
1.8 (1.4 to 2.3) |
Worsened | 12 (2.2) | 6 (9.5) | 15 (2.9) | 12 (20.0) | 0.71 | 52.5% (RRR) (−18.8% to 80.9%) |
9.5 (4.4 to 53.1) |
DRP, drug-related problem; NNT, number needed to treat; RBI, relative benefit increase; RRR, relative risk reduction.