Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 19;12:773719. doi: 10.3389/fphys.2021.773719

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Liang, Potenza, Brenna, Ma, Ren, Cheng, Ming and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effects of mitochondrial stress on hypoxia-induced TGFβ1 expression in HK2 cells. (A) Immunoblotting analysis of TGFβ1 expression in HK2 cells which were pretreated with rotenone (2 μmol/L for 1 h) and then exposed to hypoxia conditions for 48 h; the graph of right shows quantification of the signals on immunoblots; (B) cellular mitochondrial ROS generation as detected by MitoSox staining (red) followed by nuclei staining with DAPI under confocal microscope. The plot graph shows quantification of the signals. Scale bar = 29.9 μm. *p < 0.05 between the indicated groups. Student’s t-test was performed between the indicated two groups.