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. 2021 Nov 27;12:100173. doi: 10.1016/j.mtbio.2021.100173

Fig. 5.

Fig. 5

sGAG deposition in the cartilage layer scaffold seeded with FPMSCs at low and high density (FPMSCs LD and FPMSCs HD). CCs at low and high density (CC LD and CC HD) and a co-culture of FPMSCs and CCs (FPMSCs:CC). A) At day 0 a significant increase in sGAG production was observed in the CC LD group compared to the FMSCs LD group and in the CC HD group compared to other groups. B) At day 14 a significant increase in sGAG in the co-culture group was observed over all groups. C) At day 21 again the co-culture group shows significantly higher levels of sGAG production over all other groups. D) At day 28 significantly higher sGAG levels were observed in the co-culture group compared to the FPMSC LD, and CC LD groups. (∗∗∗∗p ​≤ ​0.0001, ∗∗∗p ​≤ ​0.001, ∗∗p ​≤ ​0.01, ∗p ​≤ ​0.05).