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. 2021 Nov 25;48:102198. doi: 10.1016/j.redox.2021.102198

Fig. 1.

Fig. 1

The behavior of the Nxnl2−/− mouse. Two groups of 12 Nxnl2+/+ and 12 Nxnl2−/− ♂ mice were tested at 2 months of age following an ordered pipeline as the results are reported here. Both groups are on a BALB/c background. (A) Circadian activity and water intake. (B–D) Open field. (E) String test. (F) Rotarod test. (G) Y-maze. (H) Y-maze using groups of 12 Nxnl1+/+ and Nxnl1−/− ♂ mice (BALB/c) aged of 2 months. (I) Y-maze using and additional cohort of 10 Nxnl2+/+ and 12 Nxnl2−/− ♂ mice aged of 2 months. (J) Tail suspension test. (K) Acoustic startle. (L-N) Cued and contextual fear conditioning. (O) Pentylenetetrazol (PTZ) susceptibility. (P) For water Morris maze, a novel cohort of 12 Nxnl2+/+ and 12 Nxnl2−/− ♂ mice were tested at 2 months of age was used. The data are plotted with standard of the mean (SEM). The data were analyzed by t-tests using GraphPad.