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. 2021 Aug 12;2(4):100151. doi: 10.1016/j.xinn.2021.100151

Figure 1.

Figure 1

Take a typical mouse fetus imaging for example to clarify the characteristics of MSI-based multi-modal technique

The molecular variations of mouse fetus are revealed by combing the MSI results with other analytical techniques, such as histological features, image segmentation results, 3D-MSI reconstruction, and in vivo imaging information from MRI and CT. Figures are reprinted from Anal. Chem. Guo, L., et al. 93, 4788–4793, Copyright (2021), with permission from American Chemical Society; NeuroImage. Cleary, J.O., et al. Magnetic resonance virtual histology for embryos: 3D atlases for automated high-throughput phenotyping, 54, 769–778, Copyright (2021), with permission from Elsevier; Sci. Bull. Zhao, C., et al. Airborne fine particulate matter induces cognitive and emotional disorders in offspring mice exposed during pregnancy, 66, 578–591, Copyright (2021), with permission from Elsevier; Development. Wong, M.D., et al. A novel 3D mouse embryo atlas based on micro-CT, 139, 3248–3256, Copyright (2021), with permission from the Company of Biologists Ltd.; Front. Endocrinol. Danilova, T., et al. Mesencephalic astrocyte-derived neurotrophic factor (MANF) is highly expressed in mouse tissues with metabolic function, 10, 765, Copyright (2021), with permission from Frontiers Research Foundation.