Table 2.

Inclusion and exclusion criteria adopted for the different disease cohorts

Group	Inclusion criteria	Exclusion criteria
All groups	Able to walk 4 m independently with or without walking aids Able to give informed consent Willingness to wear the sensor setups during the study Shoe size 36 European Union (EU) (3 UK) or above Able to read and write in first language of the respective country Montreal Cognitive Assessment>1555 Available for home /office visit during study period	Occurrence of any of the following 3 months prior to inclusion: myocardial infarction, hospitalisation for unstable angina, stroke, coronary artery bypass graft, percutaneous coronary intervention, implantation of a cardiac resynchronisation therapy device Current medical condition that could interfere with the patient’s compliance
COPD	≥45 years of age Diagnosis of COPD (post-bronchodilator forced expiratory volume in the first second (FEV1) to forced vital capacity ratio <0.70) Clinical stability, defined as at least 4 weeks without antibiotics and/or oral corticosteroids to treat either a moderate or severe exacerbation Current or ex-smokers with a smoking history equivalent to at least 10 pack years (1 pack year=20 cigarettes smoked per day for 1 year)	Having undergone major lung surgery (eg, lung volume reduction, lung transplant) Having a lung tumour Primary respiratory diseases other than COPD (eg, asthma) Impaired mobility related to non-COPD causes, as judged by the investigator
PD	Aged 18+ years Diagnosis of PD according to the Movement Disorders Society criteria56	Impaired mobility related to non-PD causes, as judged by the investigator
MS	Aged 18+ years Diagnosis of MS based on the revised McDonald’s criteria	Impaired mobility related to non-MS causes, as judged by the investigator
PFF	65+ years of age Surgical treatment (fixation or arthroplasty) for a low-energy fracture of the proximal femur (ICD−10 diagnosis S72.0, S72.1, S72.2) as diagnosed on X-rays of the hip and pelvis within last 12 months	Impaired mobility related to non-PFF causes, as judged by the investigator
CHF	≥45 years of age Diagnosis of chronic heart failure with a grading of II–IV of the New York Heart Association Classification	History of COPD≥GOLD III Impaired mobility related to non-CHF causes, as judged by the investigator
HA	65+ years of age

CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; HA, healthy older adults; ICD, International Classification of Disease; MS, multiple sclerosis; PD, Parkinson’s disease; PFF, proximal femoral fracture.