Table 4.
Performance measurements for patients with COPD reported by Svenningson et al. [77] before and after OPEP therapy [Republished with permission of Taylor and Francis from Svenningson et al. [77]; permission conveyed through Copyright Clearance Inc.]
| Parameter (mean ± SD) | Sputum producers (n = 14) |
Non-sputum producers (n = 13) |
|||||
|---|---|---|---|---|---|---|---|
| Pre | Post | p value | Pre | Post | p value | ||
| Lung performance | FEV1% predicted | 57 ± 20 | 59 ± 20 | 0.12 | 61 ± 17 | 59 ± 17 | 0.25 |
| FVC % predicted | 81 ± 23 | 87 ± 21 | 0.01 | 96 ± 10 | 95 ± 9 | 0.11 | |
| FEV1 /FVC | 52 ± 9 | 51 ± 9 | 0.10 | 47 ± 13 | 47 ± 13 | 0.53 | |
| Patient experience | 6MWD (m) | 370 ± 104 | 389 ± 102 | 0.04 | 412 ± 77 | 413 ± 88 | 0.97 |
| SGRQ (total score) | 49 ± 13 | 40 ± 12 | 0.01 | 35 ± 13 | 36 ± 15 | 0.64 | |
| PEQ (ease bringing up sputum) | 3.9 ± 0.8 | 2.7 ± 1.1 | 0.005 | 4.0 ± 0.4 | 3.6 ± 0.5 | 0.04 | |
| PEQ (global assessment) | 3.7 ± 0.9 | 2.9 ± 1.1 | 0.02 | 3.9 ± 0.3 | 4.1 ± 0.6 | 0.29 | |
| 3He fMRI | Ventilation defect (%) from 3He fMRI | 20 ± 9 | 19 ± 7 | 0.32 | 19 ± 13 | 21 ± 13 | 0.16 |
Data in bold font indicate statistical significance criterion (p = 0.05) met