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Efficiency of unhooking of ICLs following 1 h of treatment with 16 μM HN2. (A) NER mutants XPB mutant UV23, XPG mutant UV135, ERCC1 mutant UV96, XPF mutant UV47, and the AA8 wild-type (WT) cell line. (B) Homologous-recombination mutant XRCC2 mutant (irs1) and wild-type (WT) cell line V79. (C) XRCC3 mutant (irs1SF) and wild type (WT) cell line AA8.
