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CD7ΔCD7-CAR-T cells derived from primary T-ALL patients show robust cytotoxicity against CD7+ cells. A. Representative flow cytometric analysis show the CD7 expression in HEL and CCRF-CEM cell lines. B. Tumor cells (HEL) were pre-labeled with CFSE and plated in 24-well plates at an E:T ratio of 1:1 with different effector cells for 24 h. The mean ± SD of triplicate experiments are shown. C. Cytolysis of CD7ΔCD7-CAR-T cells against CCRF-CEM cells. ****P<0.0001.
