Table 2. Multivariable Cox Proportional Hazard Regression Analysis of Overall Mortality Hazard Ratio.

Subgroup	Hazard ratio (95% CI)
	Female patients	Male patients
Anti–PD-1
With prior ipilimumab use	1 [Reference for other female subgroups]	1 [Reference for other male subgroups]
Without prior ipilimumab use	1.06 (0.74-1.51)	1.21 (0.96-1.53)
Combination therapy with prior ipilimumab use	2.82 (1.73-4.60)	1.32 (0.94-1.87)

Abbreviation: PD-1, programmed cell death protein 1.