Table 3. Multivariable Cox Proportional Hazard Regression Analysis of Overall Mortality Hazard Ratio.

Subgroup	Female vs male patients, HR (95% CI)	P value
Anti–PD-1 therapy
With ipilimumab history	0.97 (0.68-1.38)	.85
Without ipilimumab history	0.85 (0.67-1.07)	.16
Combination therapy with ipilimumab history	2.06 (1.28-3.32)	.003

Abbreviations: HR, hazard ratio; PD-1, programmed cell death protein 1.