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. 2021 Nov;9(21):1612. doi: 10.21037/atm-21-3272

Table 2. Correlation between serum soluble leucine-rich repeats and immunoglobulin-like domains 2 (sLRIG2) and clinical factors.

Variable Total NGT Prediabetes T2DM
r P r P r P r P
Age −0.065 0.317 0.122 0.280 −0.160 0.157 −0.211 0.060
Height 0.122 0.103 0.035 0.806 −0.113 0.422 0.247 0.034
weight 0.175 0.019 −0.057 0.690 0.043 0.759 0.239 0.040
BMI 0.139 0.065 −0.107 0.454 0.090 0.525 0.146 0.219
Systolic BP 0.179 0.016 0.270 0.055 −0.088 0.528 0.185 0.114
Diastolic BP 0.216 0.004 0.236 0.096 0.153 0.269 0.197 0.092
Hemoglobin 0.109 0.128 −0.006 0.962 0.006 0.966 0.110 0.396
HbA1c 0.378 <0.001 0.021 0.856 0.060 0.603 0.375 0.001
Glucose, fasting 0.421 <0.001 −0.068 0.547 −0.181 0.107 0.499 <0.001
Glucose, PP2 0.433 <0.001 0.157 0.165 0.167 0.138 0.463 <0.001
Insulin, fasting 0.073 0.260 −0.224 0.047 −0.062 0.590 0.051 0.656
Insulin, PP2 −0.004 0.955 −0.065 0.589 0.078 0.519 −0.146 0.198
C-peptide, fasting 0.144 0.034 0.014 0.909 0.090 0.453 0.061 0.603
C-peptide, PP2 −0.001 0.988 0.107 0.376 0.136 0.259 −0.062 0.606
HOMA-IR 0.188 0.004 −0.219 0.052 −0.109 0.343 0.119 0.294
HOMA-β −0.097 0.136 −0.225 0.043 0.001 0.991 −0.139 0.218
TG 0.176 0.007 0.070 0.540 −0.001 0.995 0.168 0.153
TC −0.024 0.715 −0.086 0.452 −0.132 0.253 0.075 0.526
HDL-C −0.125 0.059 −0.253 0.025 0.027 0.814 0.067 0.574
LDL-C −0.074 0.264 0.003 0.978 −0.164 0.154 −0.071 0.555
BUN 0.101 0.131 0.005 0.963 0.088 0.449 0.093 0.441
Creatinine 0.096 0.152 0.096 0.401 0.087 0.453 0.145 0.228
eGFR 0.033 0.623 −0.102 0.370 −0.002 0.984 0.013 0.914
AST 0.118 0.076 −0.068 0.553 −0.023 0.844 0.167 0.165
ALT 0.113 0.089 −0.056 0.625 0.106 0.359 0.108 0.369

NGT, normal glucose tolerance; T2DM, type 2 diabetes mellitus; BMI, body mass index; BP, blood pressure; Hb, hemoglobin; HbA1c, glycosylated hemoglobin; PP2, 2 hour postprandial; HOMA-IR, homeostasis model assessment of insulin resistance; HOMA-β, homeostasis model assessment of β-cell function; TG, triglyceride; TC, total cholesterol; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; BUN, blood urea nitrogen; eGFR, Estimated glomerular filtration rate; AST, Aspartate aminotransferase; ALT, Alanine aminotransferase.