Table 1.

Deleterious mutation rates used in previous simulation-based analyses of inbreeding depression and genetic rescue

Study	Mutation target size	Mutation rate	Proportion deleterious	U *	UDrosophila/U†
Teixeira and Huber (11)	1,000 exons	1 × 10−5/exon/generation	0.66	0.013	92.3
Robinson et al. (74)	2,000 genes × 1,000 bp	1 × 10−8/bp/generation	0.7	0.028	42.9
Kyriazis et al. (8)	20,000 genes × 1,500 bp	1 × 10−8/bp/generation	0.77	0.462	2.6

*U is calculated as 2 × mutation target size × mutation rate × proportion of mutations that are deleterious.

^†U_Drosophila is the deleterious mutation rate per diploid genome, U_Drosophila =1.2 (15).