Table 4.
The overall clinical impression of change at the end of Day 3
| Participants’ Study ID | Levodopa (SoC) period | PF-06412562 period | ||||
|---|---|---|---|---|---|---|
| Week* | Clinician** | Caregiver*** | Week | Clinician | Caregivers | |
| 001 | 1 | 2 | 8 | 2 | 1 | 22 |
| 003 | 2 | 0 | −1 | 1 | 3 | 27 |
| 004 | 1 | −1 | −4 | 2 | 3 | 21 |
| 007 | 1 | 0 | −4 | 2 | 0 | 13 |
| 008 | 2 | 2 | 32 | 1 | 0 | 2 |
*
Week when the drug was administered/tested
**
Clinician rating on a 7 point Likert scale (−3=marked worsening; 0=no change; 3=marked improvement) (see details in Supplemental Table S3)
***
Caregiver rating is the sum [−51 (marked worsening) to[51 (marked improvement)] of 17 items listed in Supplemental Table S4 with each item on a 7 point Likert scale as above.