Table 1. Fitted Rate Constantsa.
| tau304–380_C322S | Aβ42 | |
|---|---|---|
| k+kn | <10–2 M–1 s–2b | 900 M–2 s–2 |
| k+k2 | 6 × 1011 M–3 s–2 | 4 × 1010 M–3 s–2 |
| √KM | 30 nM | >6 μM |
The products of rate constants for tau304-380_C322S and in 20 mM sodium phosphate, 0.2 mM EDTA, pH 8.0. Data for Aβ42 from ref (6) are included for comparison.
Value ill determined; only an upper limit could be determined based on the data. Best fit obtained with nc = 1.