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. 2021 Nov 26;13(11):628–649. doi: 10.4330/wjc.v13.i11.628

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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

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Sixty-five-year-old female patient with transthoracic echocardiogram finding of irregular mass originates from the right atrium wall with intracavitary expansion. Cardiovascular magnetic resonance with cine-steady state free precession images (A and B) confirms the presence of an infiltrative atrial mass in the proximity of atrio-ventricular sulcus. T1-weighted and short tau inversion recovery images (C and D, respectively) show an heterogenous hyperintense signal intensity due to complex composition of the mass. The mass shows inhomogeneous enhancement at early gadolinium enhancement and late gadolinium enhancement sequences (E and F, respectively). These findings are in keeping with a malignant primary cardiac tumor. The patient underwent myocardial biopsy with diagnosis of angiosarcoma.