Table 2.
Adverse events according to Common Terminology Criteria for Adverse Events (version 4.0)
|
Adverse event
|
Grade 1/2, n (%)
|
Grade 3, n (%)
|
| Fatigue | 24 (50.0) | |
| Diarrhea | 15 (31.3) | 2 (4.2) |
| Mucositis | 9 (18.8) | |
| Hypertransaminasemia | 7 (14.6) | 4 (8.3) |
| Thrombocytopenia | 6 (12.5) | |
| Anemia | 15 (31.2) | 2 (4.2) |
| Neutropenia | 5 (10.4) | |
| Hypothyroidism | 15 (31.3) | |
| Disgeusia | 5 (10.4) | 1 (2.1) |
| Cutaneous toxicity1 | 8 (16.7) | |
| Nausea/vomiting | 14 (29.2) | |
| Heart failure | 1 (2.1) | |
| Renal failure | 5 (10.4) | 1 (2.1) |
| Other2 | 16 (33.3) |
1
Including discoloration of hairs and cutis, hand-foot syndrome, and dermatitis.
2
Including bleeding, sleepiness, hypertrigliceridemia, hypophosphoremia, hyperbilirubinemia, loss of appetite/hyporexia, dyspepsia/epigastralgia, and hypertension.