Table 2.
Ref. | Details on study cohort | Univariate analysis for predictors of death | Multivariate analysis for predictors of death |
Regalado-Artamendi et al[40], 2021 | Lymphoma patients | Age ≥ 70 yr | Age ≥ 70 yr |
Comorbidities | Comorbidities | ||
CURB65 ≥ 3 | CURB ≥ 2 | ||
Low platelet count | Active disease | ||
Low hemoglobin level | |||
High D-dimer | |||
C-reactive protein >10 mg/dL | |||
LDH > 300 U/L | |||
Active disease1 (reference to CR) | |||
DLBCL histology (reference to FL) | |||
High-risk lymphoma2 (reference to low risk) | |||
Lamure et al[39], 2020 | Hospitalized lymphoma patients | Age ≥ 70 yr | Age ≥ 70 yr |
Hypertension | Active disease | ||
Previous cancer | |||
Bendamustine treatment | |||
Active disease |
Partial response or progression.
High risk according to prognostic index at diagnosis. CR: Complete response; CURB65: Confusion, urea concentration, respiratory rate, blood pressure and age > 65; DLBCL: Diffuse large B cell lymphoma; FL: Follicular lymphoma; LDH: Lactate dehydrogenase.