Table 2.

Pathway and Network Genes and Proteins with GWAS SNPs

Gene Symbol	Pathway or Network	Trait
APOA1	HDAC1 Network PPARA Network XBP1 Network	Very low-density lipoprotein cholesterol
ATG7	KLF15 Network Sirtuin Signaling Pathway	Fat body mass
CLIP1	Remodeling of Epithelial Adherens Junctions	Body mass index
FABP1	HDAC1 Network PPARA Network	Non-alcoholic fatty liver disease Hepatic fibrosis
GOT2	Sirtuin Signaling Pathway	Triglycerides Aspartate aminotransferase
MET	MITF Network Remodeling of Epithelial Adherens Junctions	Triglycerides
MITF	MITF Network	Low-density lipoprotein cholesterol Triglycerides
PNPLA2	PPARA Network	Body fat distribution
PPARA	PPARA Network	Type II Diabetes Total cholesterol Low-density lipoprotein cholesterol Triglycerides
RAC1	Actin Nucleation by ARP-WASP Complex Integrin Signaling Leukocyte Extravasation Signaling Paxillin Signaling	Low-density lipoprotein cholesterol
RAP1GAP	Leukocyte Extravasation Signaling	Alkaline phosphatase
SORT1	MITF Network	Type II Diabetes Coronary artery disease LDL cholesterol change
TNFRSF11B	Necroptosis Signaling Pathway	Alkaline phosphatase