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. 2021 Nov 8;17(6):1447–1547. doi: 10.5114/aoms/141941

Table I.

Classification of recommendations in the guidelines

Class of recommendation Definition Suggestion of use
Class I There is scientific evidence and/or general agreement that a specific treatment/procedure is beneficial, useful, and effective It is recommended/It is indicated
Class II Scientific evidence is ambiguous and/or there are conflicting opinions as to the usefulness/efficacy of a specific treatment/procedure
 Class IIa Prevailing evidence/opinions confirm the usefulness/efficacy of a specific treatment/procedure It should be considered
 Class IIb Evidence/opinions do not sufficiently confirm the usefulness/efficacy of a specific treatment/procedure It may be considered
Class III There is scientific evidence and/or general agreement that a specific treatment/procedure is useless/ineffective, and in certain cases it may be harmful It is not recommended