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. 2021 Nov 19;27:1609997. doi: 10.3389/pore.2021.1609997

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Copyright © 2021 Tang, Li, Liu, Liang, Hu, Shi, Zeng, Li and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ETS1 is upregulated in tumor endothelial cells in human glioblastoma. (A) Bar plots showing ETS1 expression in tumor endothelial cells (red) and non-malignant brain endothelial cells (blue) (GSE162631). (B) Expression of ETS1 in Ivy GAP RNA-seq of distinct GBM anatomic structures (One-way ANOVA with Tukey’s multiple comparisons test; *p < 0.05, ****p < 0.0001). (C) Immunohistochemical staining and quantification of ETS1 in human GBM and paired non-malignant brain tissue (bar: 50 μm) (n = 18, Mann-Whitney test, ****p < 0.0001).