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. 2020 Jun 8;58(1):538–544. doi: 10.1080/13880209.2020.1770808

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Socheongryongtang down-regulated the expression of CXCL1, CCL-2 and CCR2. (A) Socheongryongtang statistically significantly inhibited the DNA level of CXCL1 and trended towards suppressing the levels of CCL-2 and CCR2. (B) Socheongryongtang significantly suppressed the CXCL1 expression with 150 mg/kg treatment to an extent similar to that by Spiriva treatment. Socheongryongtang down-regulated the expression of CCL2 (C) and CCR2 (D). Each bar represents the mean ± SD (N = 8). Arrow, positive cells. *p < 0.05 vs. control group; ^$p < 0.05 vs. LPS intranasal instillation group; ^#p < 0.05 vs. Spiriva treatment group. Magnification, ×200.