Table 2.
Characteristics of patients who experienced a major bleed
| Age/Sex | Invasive Mechanical Ventilation at Bleed? | Vasopressors at Bleed? | Site of Bleed(s) | Days from tPA to Bleed | Days from tPA to Death | On Therapeutic Anticoagulation at Bleed? | PTT at Bleed (s) | INR at Bleed | Platelet Count at Bleed (109/L) | pRBC Units Administered* | Invasive Hemostatic Intervention Performed? | Fatal or Important Contributor to Death? |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 57/M | Yes | Yes | NP | 2 | 21 | Yes, enoxaparin |
79 | 1.4 | 120 | 2 | Yes | No |
| 58/M | Yes | No | Bronchopulmonary | 1 | 8 | Yes, heparin infusion |
66 | 1.3 | 200 | 0 | Yes | No |
| 46/M | Yes | Yes | Bronchopulmonary and GI | 0 | 0 | No (receiving prophylactic-dose heparin) | 39 | 1.1 | 205 | 0 | No | Yes |
| 37/M | Yes | Yes | Intracranial | 6 | 6 | Yes, enoxaparin |
32 | 1.4 | 391 | 0 | No | Yes |
| 47/F | Yes | Yes | NP and OP | 0 | 19 | Yes, heparin infusion |
70 | 1.1 | 149 | 1 | No | No |
| 59/M | Yes | Yes | Intracranial | 4 | 4 | Yes, heparin infusion |
68 | 1.2 | 138 | 1 | No | Yes |
Definition of abbreviations: GI = gastrointestinal; INR = international normalized ratio; NP = nasopharyngeal; OP = oropharyngeal; pRBC = packed red blood cells; PTT = partial thromboplastin time; tPA = tissue plasminogen activator.
*
pRBC transfusion was assessed within 2 days after the bleed.