Figure 5.
The swing movement during cautious locomotion is well organized in wild-type mice but is more variable in the absence of proprioceptive sensory feedback from the muscle spindles. A, Histogram representing the distribution of HLAP in swing movements during cautious locomotion in wild-type (left) and Egr3-KO (right) mice. B, Histogram showing the distribution of FLPP in swing movements during cautious locomotion in wild-type (left) and Egr3-KO (right) mice. C, Histogram showing the distribution of the distance between the HLAP and FLPP in swing movements during cautious locomotion in wild-type (left) and Egr3-KO (right) mice. D, Diagram illustrating the relationship between the average (±SD) of the HLAP and FLPP during normal swing movements (norm) and swing movements during cautious locomotion (caut) in wild-type (left) and Egr3-KO (right) mice during SCRs. **p < 0.01, ***p < 0.001. Histograms illustrating the distribution of FLPP during cautious locomotion in individual WT and Egr3-KO mice are shown in Extended Data Figure 5-1.