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. 2021 Nov 29;10:e64688. doi: 10.7554/eLife.64688

Figure 7. Contribution of PDP1 and UBIAD1 to the feedback regulatory system that targets HMG CoA reductase ERAD to control synthesis of GGpp.

Figure 7.

The synthesis and hydrolysis of GGpp are key focal points in the feedback regulation of the nonsterol branch of the mevalonate pathway (see text for details).