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. 2021 Nov 22;22(12):1515–1523. doi: 10.1038/s41590-021-01066-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 1 — Fold change in a and c, FcγR2A, and b and d, FcγR3A binding antibodies to PPD, LAM, PstS1, Apa, and HspX in the a and b, plasma, and c and d, BAL of each BCG-vaccinated rhesus macaque. Fold changes were calculated as fold change in Luminex median fluorescence intensity (MFI) over the pre-vaccination level for each macaque. A base-2 log scale is used for the y-axis. Each point represents the duplicate average from a single macaque. The lines show group medians over time. Kruskal-Wallis with Dunn’s multiple-comparison tests were performed on the fold change values at each timepoint, comparing each experimental BCG vaccination group to the standard-dose i.d. BCG group. Adjusted p-values < 0.05 compared to the standard-dose i.d. BCG group are shown and are colored by vaccination group.

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