Fig. 3.

The AUROC values reported for 10 of the included models. The models are grouped by the type of risk factor; within each group, the models are ordered by the number of risk factors included in the model (left to right). The groups are labelled as follows: A—genetic risk factors, B—demographic and lifestyle risk factors, C—demographic and lifestyle risk factors combined with biomarkers, and D—only biomarkers. The type of model (development, and internal and external validation), sex of the population used, and inclusion of age as a risk factor are indicated in the figure. AUROC = area under the receiver-operating curve.