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. 2021 Dec 4;158:61–69. doi: 10.1016/j.maturitas.2021.11.015

Table 3.

Odds ratios of infection severity according to sex and age groups in Sample A (N = 6873).

Sample A° Negative NPS test N = 5,171 (75.2) Asymptomatic or mild infection N = 1,214 (17.7) Severe infection N = 488 (7.1)
N (%) OR (95% CI) N (%) OR (95% CI) N (%)
Males 1,675 (34.4) 1 (ref.)
411 (33.9) 1 (ref.)
266 (54.5)
Females 3,496 (67.6) 0.92 0.79–1.06 803 (66.1) 0.46 0.37–0.57 222 (45.5)
SEX X AGE
Males aged≥60 391 (7.6)
1 (ref.)
120 (9.9) 1 (ref.)
118 (24.2)
Males aged 50–59 411 (8.0) 0.96 0.69–1.34 103 (8.5) 0.74 0.51–1.08 82 (16.8)
Males aged <50 873 (16.9) 0.85 0.63–1.16 188 (15.5) 0.34 0.23–0.50 66 (13.5)
Females aged≥60 428 (8.3) 1.15 0.87–1.53 187 (15.4) 0.58 0.41–0.82 80 (16.4)
Females aged 50–59 977 (18.9) 0.77 0.57–1.04 208 (17.3) 0.33 0.22–0.48 75 (15.4)
Females aged <50 2,091 (40.4) 0.77 0.58–1.02 408 (33.6) 0.15 0.10–0.22 67 (13.7)

Males and negative NPS test as reference category. Asymptomatic or mild infection (positive NPS test without symptoms or with at least one COVID-19 like symptom) and severe infection (positive NPS test with pneumonia and/or hospitalization for COVID-19).

Model adjusted for age°, education, employment status, area of residence, healthcare professionals, physical activity, smoking status, living with at risk co-habitants, contact with COVID-19 cases, heart diseases, hypertension, depression, renal diseases, immune system disorders, flu and anti-pneumococcal vaccine, thyroid drugs, anti-inflammatory drugs, and self-perceived health status.