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. Author manuscript; available in PMC: 2022 Dec 2.
Published in final edited form as: Structure. 2021 Sep 11:S0969-2126(21)00261-6. doi: 10.1016/j.str.2021.07.011

Figure 2. Crystal structure of the TAZ1:fusion peptide complex and conformation of the TAZ1 α4 helix.

Figure 2.

(A) Crystal structure of the TAZ1:fusion peptide complex. TAZ1 is shown in salmon and the fusion peptide is shown in slate. Zinc atoms are shown as gray spheres. TAZ1 and fusion peptide helices and N- and C-termini are labeled for reference. (B) Superpositions of the TAZ1 α4 helix from the TAZ1:CITED2 (cyan), TAZ1:HIF-1α (tan), and TAZ1:fusion peptide (salmon) structures. Structures were aligned based on residues from the TAZ1 α1 (residues 350–363), α2 (residues 383–397), and α3 (residues 407–420) helices. Residues 426–437, encompassing the TAZ1 α4 helix, are shown.