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. 2021 Sep 2;35(12):1289–1301. doi: 10.1007/s40263-021-00856-3
Adjunctive brivaracetam (BRV) improved seizure frequency in patients with focal epilepsy irrespective of levetiracetam history.
Seizure response was higher among patients treated with BRV and concomitant sodium channel blockers (SCBs).
Adverse events were less frequently observed when BRV was concomitantly administered with SCBs than with no SCBs.