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. 2021 Jul 14;11(11):3508–3526. doi: 10.1016/j.apsb.2021.07.006

Figure 3.

Figure 3

Five week-old WT, Ampkα2−/−, Akt2−/−, and DKO mice were placed on a 45% high fat (HF) or nutritionally matched low fat (LF) diet for 20 weeks. (a) Representative photographs of mice (prone and supine positions) and white adipose tissues. (b) Food intake (per mouse daily, P > 0.05). (c) Trajectory of body weight of WT and DKO mice. (d) Intraperitoneal glucose tolerance test (IPGTT). (e) Area under curve (AUC) for IPGTT. (f) Serum insulin level. (g) Lean mass weight. (h) Lean mass percentage. (i) Fat mass weight. (j) Fat mass percentage. Data are expressed as mean ± SEM (n = 11–13 for panels b–e, n = 7 for panels f–j). ∗P < 0.05 vs. WT mice; #P < 0.05 vs. WT-HF mice; P < 0.05 vs. DKO-HF mice.